Similac NeoSure Post-NICU Premature Infant Formula Powder | Catch-Up Growth

After weeks or months in the NICU, your premature baby is finally coming home — and the work of catch-up growth is just beginning. Similac NeoSure® is Abbott's clinically developed post-discharge formula specifically designed for premature and low birth weight infants, delivering higher calories, more protein, and greater bone-building mineral density than any standard term infant formula. Because your preemie's first months at home are just as critical as their time in the NICU.

Key Features & Benefits

• Higher Calories & Protein for Accelerated Catch-Up Growth: Delivers more calories and protein per serving than standard 20 kcal/fl oz formula — closing the growth gap faster for preemies who left the NICU below expected milestones.
• Enhanced Calcium, Phosphorus & Vitamin D for Bone Development: Premature infants are at significant risk for metabolic bone disease. NeoSure's elevated mineral profile directly addresses this critical vulnerability.
• DHA & ARA for Neurological Development: Essential fatty acids that support the accelerated brain and visual development premature infants require — especially important given the neurological demands of early extrauterine life.
• Clinically Studied Post-Discharge Formula: NeoSure has been the subject of multiple clinical trials demonstrating effectiveness in supporting weight, length, and head circumference catch-up growth in preterm infants.
• #1 Fed in Hospitals: Alongside EnfaCare, NeoSure is one of the two most commonly used post-discharge formulas at NICU discharge — a testament to its established clinical track record.
• 2-Pack & 6-Pack Options: Stock up for consistent catch-up growth support without gaps in supply.

Technical Specs

• Age Range: Premature/low birth weight infants through catch-up growth period
• Can Size: 13.1 oz powder
• Caloric Density: Higher than standard 20 kcal/fl oz formula
• Key Nutrients: DHA, ARA, Calcium, Phosphorus, Vitamin D, Iron
• Manufacturer: Abbott / Similac
• Available Quantities: 2-pack ($49.99) | 6-pack case ($149.99)

How long should my preemie stay on Similac NeoSure?

Most neonatologists recommend continuing NeoSure until your baby reaches their corrected age of 9–12 months, or until adequate catch-up growth is confirmed by your pediatrician. Transitioning too early can stall the growth trajectory NeoSure is designed to support.

What is the difference between Similac NeoSure and Enfamil NeuroPro EnfaCare?

Both are post-discharge premature formulas, but NeuroPro EnfaCare adds MFGM and Choline for enhanced brain development. NeoSure focuses on caloric density, protein, and mineral profile for physical catch-up growth. Your NICU team will recommend the best fit based on your baby's individual discharge profile.

Can Similac NeoSure be mixed with breast milk?

Yes. NeoSure powder can be mixed with expressed breast milk to fortify caloric and nutrient density for partially breastfed preemies. Always follow your NICU dietitian's specific instructions for the correct powder-to-milk ratio to avoid over-fortification.

You May Also Consider

• Enfamil NeuroPro EnfaCare — Post-NICU premature formula with MFGM, DHA and higher calories for catch-up growth with added brain development support.
• Nutricia Fortini 30 kcal/fl oz — The highest-calorie ready-to-feed option for infants needing maximum energy density for rapid catch-up growth.
• Enfamil Infant Formula — The standard formula your preemie may graduate to once catch-up growth milestones are confirmed by your pediatrician.